Comparison 7. Chemotherapy with capecitabine versus 5‐FU‐containing regimes.
Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
---|---|---|---|---|
1 Overall Survival | 5 | 732 | Hazard Ratio (Fixed, 95% CI) | 0.94 [0.79, 1.11] |
2 Tumour response | 4 | 636 | Odds Ratio (M‐H, Random, 95% CI) | 0.85 [0.40, 1.79] |
3 Time to progression | 1 | Hazard Ratio (Fixed, 95% CI) | Subtotals only | |
4 Progression‐free survival | 4 | 647 | Hazard Ratio (Random, 95% CI) | 0.98 [0.77, 1.23] |
5 Treatment‐related death | 2 | 481 | Odds Ratio (M‐H, Random, 95% CI) | 1.88 [0.23, 15.15] |
6 Treatment discontinuation due to toxicity | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Subtotals only |