Comparison 8. Chemotherapy with oxaliplatin versus the same regime including cisplatin.
Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
---|---|---|---|---|
1 Overall Survival | 5 | 1105 | Hazard Ratio (Random, 95% CI) | 0.81 [0.67, 0.98] |
2 Tumour response | 5 | 1081 | Odds Ratio (M‐H, Fixed, 95% CI) | 1.38 [1.08, 1.76] |
3 Progression‐free survival | 4 | 1034 | Hazard Ratio (Random, 95% CI) | 0.88 [0.66, 1.19] |
4 Treatment‐related death | 5 | 1132 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.47 [0.17, 1.30] |
5 Treatment discontinuation due to toxicity | 3 | 970 | Odds Ratio (M‐H, Random, 95% CI) | 0.97 [0.44, 2.13] |