Comparison 9. Taxane‐platinum‐fluoropyrimidine combinations versus taxane‐platinum (without fluoropyrimidine).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall survival	3	482	Hazard Ratio (Fixed, 95% CI)	0.86 [0.71, 1.06]
2 Tumour response	3	482	Odds Ratio (M‐H, Fixed, 95% CI)	2.08 [1.37, 3.15]
3 Progression‐free survival	3	482	Hazard Ratio (Fixed, 95% CI)	0.74 [0.59, 0.93]
4 Treatment‐related death	3	482	Odds Ratio (M‐H, Fixed, 95% CI)	1.95 [0.73, 5.17]
5 Treatment discontinuation due to toxicity	2	234	Odds Ratio (M‐H, Fixed, 95% CI)	1.71 [0.79, 3.69]