Skip to main content
. 2019 Apr 25;14(4):e0215535. doi: 10.1371/journal.pone.0215535

Table 1. The kinetic parameters and affinity constants of mAbs 3G11 and 5H5 for binding with linear tri- (G3), penta- (G5) and nonaglucoside (G9) and branched octaglucoside brG8.

mAb Synthetic glucosides
G3 G5 brG8 G9
3G11 KD > 1 mM KD = 12 ± 1 nM KD > 1 mM KD = 11 ± 1 nM
ka = 6.4 × 104 M-1s-1 ka = 8.2 × 104 M-1s-1
kd = 8.5 × 10−4 s-1 kd = 8.8 × 10−4 s-1
5H5 KD = 9.0 ± 3.0 nM KD = 4.0 ± 0.5 nM KD = 4.5 ± 0.5 nM KD = 1.9 ± 0.2 nM
ka = 7.2 × 104 M-1s-1 ka = 1.4 × 105 M-1s-1 ka = 1.7 × 105 M-1s-1 ka = 4.2 × 105 M-1s-1
kd = 6.3 × 10−4 s-1 kd = 5.6 × 10−4 s-1 kd = 7.8 × 10−4 s-1 kd = 8.1 × 10−4 s-1