Fig. 3.

Age related alterations of regional topological properties in AOS. (A) Age-related associations between nodal properties of the left hippocampus in AOS and HC subjects. Black hollow dots mark the outliers point in the linear estimation using Shepherd’s pi correlation. (B) Topological properties comparison in the age subgroups. ANOVA test was used to investigate the interactions between age (“12–14,” “15–16,” and “17–18”) and “diagnosis” (AOS, HC). Group comparison in each age subgroup was examined using permutation tests. Error bars indicate standard deviations. AOS, adolescent-onset schizophrenia; HC, healthy controls.