Table 3.

Difference Between SCZ and HV [¹¹C]FLB 457 ΔBP_ND in ROIs

	SCZ (ΔBPND)	HV (ΔBPND)	t	P
DLPFC	−7.79 ± 11.28	−0.58 ± 8.45	1.84	.079
ACC	−11.48 ± 15.08	4.40 ± 6.00	3.52	.003a
Occipital cortex	−1.83 ± 12.48	3.17 ± 15.57	0.90	.37
Inferior Parietal cortex	−3.35 ± 13.42	6.06 ± 28.77	1.06	.30
Temporal cortex	1.44 ± 15.58	0.03 ± 9.01	0.28	.78
Thalamus	−8.73 ± 19.50	−3.28 ± 18.36	0.71	.48

P significant at <.05; t, independent t test.

Note: Abbreviations are explained in the footnotes to tables 1 and 2.

^aPositive value in ΔBP_ND indicates decrease in the BP_ND during WCST compared with BP_ND during SMCT which in turn suggests increased dopamine release during WCST compared with SMCT. On the other hand, negative value in ΔBP_ND indicate increase in the BP_ND during WCST compared with BP_ND during SMCT which in turn suggests dopamine depletion.