Nuraei 2010.
Methods | Design: randomized controlled trial Withdrawals: none Setting: single centre, Iran Sample size: 108 |
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Participants | Age (mean): 38/39 years Gender (M/F): 68/40 ASA grade: "I and II" ‐ NB: All participants had end‐stage renal disease and were awaiting transplant. Surgery type: renal transplant surgery Surgery duration (mean): 2.1/2.0 hours Anaesthesia type: general |
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Interventions |
Intervention n = 54 Buffered arm ‐ Ringer's lactate Control n = 54 Non‐buffered arm ‐ normal saline Protocol for fluid administration not reported Co‐interventions: none |
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Outcomes | Renal function, acid‐base status up to 24 hours after surgery | |
Notes | Funding source: not disclosed Declarations of interest: none disclosed |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Randomized double‐blinded trial |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Double‐blinded |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | All outcomes adequately reported |
Selective reporting (reporting bias) | Low risk | No evidence of selection bias. All proposed outcome measures adequately reported |
Other bias | Low risk | No other obvious bias |