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. 2017 Sep 21;2017(9):CD004089. doi: 10.1002/14651858.CD004089.pub3

Nuraei 2010.

Methods Design: randomized controlled trial
Withdrawals: none
Setting: single centre, Iran
Sample size: 108
Participants Age (mean): 38/39 years
Gender (M/F): 68/40
ASA grade: "I and II" ‐ NB: All participants had end‐stage renal disease and were awaiting transplant.
Surgery type: renal transplant surgery
Surgery duration (mean): 2.1/2.0 hours
Anaesthesia type: general
Interventions Intervention n = 54
Buffered arm ‐ Ringer's lactate
Control n = 54
Non‐buffered arm ‐ normal saline
Protocol for fluid administration not reported
Co‐interventions: none
Outcomes Renal function, acid‐base status up to 24 hours after surgery
Notes Funding source: not disclosed
Declarations of interest: none disclosed
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomized double‐blinded trial
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Double‐blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk All outcomes adequately reported
Selective reporting (reporting bias) Low risk No evidence of selection bias. All proposed outcome measures adequately reported
Other bias Low risk No other obvious bias