Comparison 6.

Mifepristone (all doses) versus Yuzpe

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Observed number of pregnancies (all women)	3	2144	Risk Ratio (M‐H, Fixed, 95% CI)	0.14 [0.05, 0.41]
2 Observed number of pregnancies (by risk status)	1	800	Risk Ratio (M‐H, Fixed, 95% CI)	0.10 [0.01, 1.90]
2.1 High‐risk women	1	322	Risk Ratio (M‐H, Fixed, 95% CI)	0.10 [0.01, 1.90]
2.2 Low‐risk women	1	478	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Observed number of pregnancies (time from intercourse)	1	958	Risk Ratio (M‐H, Fixed, 95% CI)	0.19 [0.06, 0.59]
3.1 within 24 h	1	269	Risk Ratio (M‐H, Fixed, 95% CI)	0.14 [0.01, 2.72]
3.2 25‐48 h	1	429	Risk Ratio (M‐H, Fixed, 95% CI)	0.15 [0.02, 1.18]
3.3 49‐72 h	1	260	Risk Ratio (M‐H, Fixed, 95% CI)	0.24 [0.05, 1.16]
4 Need for extra dose	1	958	Risk Ratio (M‐H, Fixed, 95% CI)	0.11 [0.03, 0.49]
5 Any side effect	2	1693	Risk Ratio (M‐H, Fixed, 95% CI)	0.83 [0.77, 0.88]
6 Specific side effects	3		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
6.1 Nausea	3	2186	Risk Ratio (M‐H, Random, 95% CI)	0.63 [0.53, 0.76]
6.2 Vomiting	3	2186	Risk Ratio (M‐H, Random, 95% CI)	0.12 [0.07, 0.20]
6.3 Headache	2	1800	Risk Ratio (M‐H, Random, 95% CI)	0.75 [0.61, 0.91]
6.4 Dizziness	1	1000	Risk Ratio (M‐H, Random, 95% CI)	0.58 [0.42, 0.80]
6.5 Fatigue	1	1000	Risk Ratio (M‐H, Random, 95% CI)	0.81 [0.68, 0.95]
6.6 Breast tenderness	3	2186	Risk Ratio (M‐H, Random, 95% CI)	0.86 [0.54, 1.39]
6.7 Spotting/bleeding after treatment	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
6.8 Abdominal pain	1	1000	Risk Ratio (M‐H, Random, 95% CI)	0.76 [0.61, 0.95]
6.9 Hot flushes	1	1000	Risk Ratio (M‐H, Random, 95% CI)	0.58 [0.40, 0.83]
6.10 Lethargy	1	1000	Risk Ratio (M‐H, Random, 95% CI)	0.75 [0.59, 0.95]
7 Menses	3		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
7.1 Early	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
7.2 Delay	3	1924	Risk Ratio (M‐H, Fixed, 95% CI)	2.83 [2.30, 3.47]