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. 2017 Aug 2;2017(8):CD001324. doi: 10.1002/14651858.CD001324.pub5

Comparison 8.

Mifepristone alone (low or mid dose) versus mifepristone + anordrin (all doses)

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Observed number of pregnancies (all women) 5 3038 Risk Ratio (M‐H, Fixed, 95% CI) 1.32 [0.73, 2.41]
2 Any side effect 2 442 Risk Ratio (M‐H, Fixed, 95% CI) 0.83 [0.49, 1.41]
3 Specific side effects 5 Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.1 Nausea 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 0.53 [0.44, 0.65]
3.2 Vomiting 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 0.26 [0.14, 0.50]
3.3 Headache 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 0.81 [0.53, 1.25]
3.4 Dizziness 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 0.77 [0.54, 1.10]
3.5 Breast tenderness 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 0.93 [0.65, 1.32]
3.6 Fatigue 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 0.66 [0.49, 0.89]
3.7 Diarrhoea 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.8 Spotting/bleeding after treatment 5 3038 Risk Ratio (M‐H, Fixed, 95% CI) 1.80 [1.33, 2.43]
3.9 Abdominal pain 1 2387 Risk Ratio (M‐H, Fixed, 95% CI) 1.18 [0.83, 1.67]
4 Delay in menses 3 Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.1 Early 0 0 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.2 Delay 3 2781 Risk Ratio (M‐H, Fixed, 95% CI) 0.79 [0.65, 0.97]