Comparison 22.

Mifepristone mid dose (50 mg) versus mifepristone mid dose (25 mg)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Observed number of pregnancies (all women)	13	3123	Risk Ratio (M‐H, Fixed, 95% CI)	0.72 [0.41, 1.27]
2 Any side effect	6	1465	Risk Ratio (M‐H, Fixed, 95% CI)	1.79 [1.39, 2.31]
3 Specific side effects	3		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 Nausea	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	0.92 [0.44, 1.91]
3.2 Vomiting	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	0.20 [0.01, 4.10]
3.3 Headache	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	0.74 [0.17, 3.28]
3.4 Dizziness	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	1.49 [0.54, 4.10]
3.5 Fatigue	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	2.97 [0.12, 72.53]
3.6 Breast tenderness	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	0.40 [0.08, 2.02]
3.7 Abdominal pain	1	418	Risk Ratio (M‐H, Fixed, 95% CI)	2.10 [0.93, 4.77]
3.8 Spotting/bleeding after treatment	2	617	Risk Ratio (M‐H, Fixed, 95% CI)	1.35 [0.82, 2.20]
3.9 Early menses	1	178	Risk Ratio (M‐H, Fixed, 95% CI)	1.8 [0.63, 5.16]
4 Delay in menses	8	1945	Risk Ratio (M‐H, Fixed, 95% CI)	1.32 [1.12, 1.56]
4.1 > 3 days	3	816	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.75, 1.34]
4.2 > 5 days	1	92	Risk Ratio (M‐H, Fixed, 95% CI)	1.04 [0.45, 2.39]
4.3 > 7 days	4	1037	Risk Ratio (M‐H, Fixed, 95% CI)	1.57 [1.26, 1.94]