Comparison 25.

Mifepristone high dose (> 50 mg) versus mifepristone mid dose (25‐50 mg)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Observed number of pregnancies (all women)	9	3009	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.50, 1.72]
2 Any side effect	5	1310	Risk Ratio (M‐H, Random, 95% CI)	2.64 [1.57, 4.43]
3 Specific side effects	5		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 Nausea	1	90	Risk Ratio (M‐H, Fixed, 95% CI)	1.25 [0.36, 4.35]
3.2 Dizziness	1	90	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.21, 4.69]
3.3 Fatigue	1	90	Risk Ratio (M‐H, Fixed, 95% CI)	2.0 [0.19, 21.28]
3.4 Breast tenderness	1	90	Risk Ratio (M‐H, Fixed, 95% CI)	2.0 [0.19, 21.28]
3.5 Diarrhoea	1	90	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.21, 4.69]
3.6 Spotting/bleeding after treatment	4	1509	Risk Ratio (M‐H, Fixed, 95% CI)	1.32 [1.12, 1.56]
4 Menses	8		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 Early	2	290	Risk Ratio (M‐H, Fixed, 95% CI)	10.0 [1.30, 76.66]
4.2 Delay	8	2854	Risk Ratio (M‐H, Fixed, 95% CI)	1.53 [1.34, 1.75]