Methods |
Double‐blind, randomised, multicentre trial Random number generation done centrally. Double‐blinded by use of identical placebos |
Participants |
1209 women attending the family planning clinics in 11 provinces of China. Women had regular menstrual periods and attended the clinic within 72 h of a single act of unprotected intercourse |
Interventions |
Mife 25 mg vs Mife 10 mg, single dose |
Outcomes |
Observed number of pregnancies, side effects and changes in menstrual pattern |
Notes |
Total of 85 cases lost to follow‐up or missed data (7.03%)
Observed pregnancy/expected pregnancy/total number women: Mife 25 mg 5/91/579; Mife 10 mg 12/78/545
|
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Random number generation done centrally |
Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes |
Low risk |
Double‐blind |
Incomplete outcome data (attrition bias) All outcomes |
Low risk |
Lost to follow‐up reported |
Selective reporting (reporting bias) |
Low risk |
Reported planned outcomes |
Other bias |
Low risk |
None detected |