Rowlands 1983

Methods	Women randomly allocated to 2 treatments. Side effects assessed through interviews with the women
Participants	101 healthy women attending a family planning clinic (Margaret Pyke Centre) in London, UK Included women who had had unprotected intercourse within 120 h (included some women who had had multiple acts of unprotected intercourse)
Interventions	Yuzpe (ethinyl oestradiol 100 μg + norgestrel 1 mg, repeated after 12 h) vs danazol 400 mg, repeated after 12 h
Outcomes	Observed number of pregnancies, side effects and changes in menstrual pattern
Notes	Additional data provided by the study authors. 6 women in the danazol group and 12 in the Yuzpe group were excluded after randomisation
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method of sequence generation was not stated "Patients were randomly assigned"
Allocation concealment (selection bias)	Unclear risk	Method of allocation concealment was not stated
Blinding (performance bias and detection bias) All outcomes	Unclear risk	No explanation of blinding was provided
Incomplete outcome data (attrition bias) All outcomes	Low risk	"One woman was lost to follow‐up. Data for six further women are incomplete as they were not seen at follow‐up; contact was made by telephone or post." Explains lost numbers
Selective reporting (reporting bias)	Unclear risk	Planned outcomes to report were not clearly outlined in the methods and no protocol available.
Other bias	Low risk	None detected