Methods | Randomised, double‐blind, multicentre trial. Random number generation done centrally, double‐blinded by use of identical placebos | |
Participants | 200 healthy women recruited in the study from an obs/gyn clinic in Wuhan, China Included women with regular menstrual periods, aged 22‐42 years, who had attended the clinic within 72 h of a single act of unprotected intercourse Excluded women who were on hormonal contraception in the current cycle and those with uncertain dates of last menstrual period |
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Interventions | Mife 10 mg, single dose vs Mife 25 mg, orally | |
Outcomes | Observed number of pregnancies, side effects and changes in menstrual pattern | |
Notes |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Random number generation done centrally |
Allocation concealment (selection bias) | Unclear risk | Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes | Low risk | Double‐blind |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Post‐randomisation exclusion and loss to follow‐up not reported |
Selective reporting (reporting bias) | Low risk | Reported planned outcomes |
Other bias | Low risk | None detected |