Methods |
Women randomly allocated to 2 groups. Method of randomisation not reported |
Participants |
100 women attending in an obs/gyn clinic, No. 5 hospital, Haerbin Medical University, China. Women had regular menstrual periods and a single act of unprotected intercourse within 72 h of attending the clinic |
Interventions |
Mife 25 mg vs Mife 10 mg, single dose, orally |
Outcomes |
Observed number of pregnancies, side effects and changes in menstrual pattern |
Notes |
Observed pregnancy/total number of women: Mife 25 mg 1/50; Mife 10 mg 1/50
-
Side effects:
Mife 25 mg: nausea and vomiting 3/50; dizziness 2/50; breast tenderness 1/50; fatigue 2/50; diarrhoea 3/50
Mife 10 mg: nausea and vomiting 2/50; dizziness 1/50; breast tenderness 1/50; fatigue 2/50; diarrhoea 2/50
-
Changes in menstrual pattern:
Early: Mife 25 mg 1/49; Mife 10 mg 1/49
Delay: Mife 25 mg 6/49; Mife 10 mg 5/49
Spotting: Mife 25 mg 1/49; Mife 10 mg 1/49
|
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Mentioned randomisation but description not adequate |
Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk |
Not mentioned |
Incomplete outcome data (attrition bias) All outcomes |
Unclear risk |
No mention of post‐randomisation exclusion and loss to follow‐up |
Selective reporting (reporting bias) |
Low risk |
Reported planned outcomes |
Other bias |
Low risk |
None detected |