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. 2017 Aug 2;2017(8):CD001324. doi: 10.1002/14651858.CD001324.pub5
Methods Women randomly allocated to 2 groups. Method of randomisation not reported
Participants 100 women attending in an obs/gyn clinic, No. 5 hospital, Haerbin Medical University, China. Women had regular menstrual periods and a single act of unprotected intercourse within 72 h of attending the clinic
Interventions Mife 25 mg vs Mife 10 mg, single dose, orally
Outcomes Observed number of pregnancies, side effects and changes in menstrual pattern
Notes
  1. Observed pregnancy/total number of women: Mife 25 mg 1/50; Mife 10 mg 1/50

  2. Side effects:

    1. Mife 25 mg: nausea and vomiting 3/50; dizziness 2/50; breast tenderness 1/50; fatigue 2/50; diarrhoea 3/50

    2. Mife 10 mg: nausea and vomiting 2/50; dizziness 1/50; breast tenderness 1/50; fatigue 2/50; diarrhoea 2/50

  3. Changes in menstrual pattern: 

    1. Early: Mife 25 mg 1/49; Mife 10 mg 1/49

    2. Delay: Mife 25 mg 6/49; Mife 10 mg 5/49

    3. Spotting: Mife 25 mg 1/49; Mife 10 mg 1/49

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Mentioned randomisation but description not adequate
Allocation concealment (selection bias) Unclear risk Method of allocation concealment not mentioned
Blinding (performance bias and detection bias) All outcomes Unclear risk Not mentioned
Incomplete outcome data (attrition bias) All outcomes Unclear risk No mention of post‐randomisation exclusion and loss to follow‐up
Selective reporting (reporting bias) Low risk Reported planned outcomes
Other bias Low risk None detected