Methods | Double‐blind, randomised trial. Random number generation done centrally. Double‐blinded by use of identical placebos. Allocation concealment achieved by sealed, sequentially numbered, tinted bottles filled and labelled by the manufacturer | |
Participants | 1324 women in 16 urban family planning clinics in China Included only women who came within 72 h of unprotected intercourse Excluded women with irregular menstrual periods, with multiple acts of intercourse, on oral contraceptives and post‐abortal women whose menstrual periods had not returned to normal |
|
Interventions | LNG 0.75 mg, 2 doses, 12 h apart vs Mife 10 mg, single dose | |
Outcomes | Observed number of pregnancies, side effects and changes in menstrual pattern | |
Notes |
|
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Random number generation done centrally |
Allocation concealment (selection bias) | Low risk | Allocation concealment achieved by sealed, sequentially numbered, tinted bottles filled and labelled by the manufacturer |
Blinding (performance bias and detection bias) All outcomes | Low risk | Double‐blind |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Post‐randomisation exclusion and loss to follow‐up reported |
Selective reporting (reporting bias) | Low risk | Reported planned outcomes |
Other bias | Low risk | None detected |