Methods | Women 'randomly allocated' to 4 groups. Method of randomisation not reported | |
Participants | 358 healthy women recruited into the study from clinics of MCH hospital in Guangzhou, China Included women with regular menstrual periods, aged 17‐46 years, who had attended the clinic within 72 h of a single act of unprotected intercourse and they were willing to use condom for further acts of unprotected coitus during that cycle Excluded women on hormonal contraception in the current cycle and those with uncertain dates of last menstrual period |
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Interventions | Mife 25 mg twice, 12 h apart vs anordrin 7.5 mg, twice, 12 h apart vs danazol 400 mg, twice, 12 h apart | |
Outcomes | Observed number of pregnancies, side effects and changes in menstrual pattern | |
Notes |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Mentioned randomisation but description not adequate |
Allocation concealment (selection bias) | Unclear risk | Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | No mention of post‐randomisation exclusion and loss to follow‐up |
Selective reporting (reporting bias) | Low risk | Reported planned outcomes |
Other bias | Low risk | None detected |