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. 2017 Aug 2;2017(8):CD001324. doi: 10.1002/14651858.CD001324.pub5

Zeng 2007

Methods Women allocated to 2 groups. The method of allocation was not reported
Participants 100 women attending in a county hospital, Zhejiang, China. Women had regular menstrual periods and a single act of unprotected intercourse within 120 h of attending the clinic
Interventions Mife 25 mg + MTX 5 mg vs Mife 25 mg, single dose, orally
Outcomes Observed number of pregnancies, side effects and changes in menstrual pattern
Notes

  1. Observed pregnancy/total number of women: Mife + MTX: 0/50; Mife: 1/50

  2. Side effects:

    1. Nausea and vomiting: Mife + MTX 6/50; Mife 5/50

  3. Changes in menstrual pattern: 

    1. Delay: Mife + MTX 22/50; Mife 20/49
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Mentioned randomisation but description not adequate
Allocation concealment (selection bias) Unclear risk Method of allocation concealment not mentioned
Blinding (performance bias and detection bias) All outcomes Unclear risk Not mentioned
Incomplete outcome data (attrition bias) All outcomes Unclear risk No mention of post‐randomisation exclusion and loss to follow‐up
Selective reporting (reporting bias) Low risk Reported planned outcomes
Other bias Low risk None detected