Methods |
Women 'randomly allocated' into 4 groups |
Participants |
782 women attending a hospital clinic in Qinhai, China. Women had regular menstrual periods and attended the clinic within 72 h of a single act of unprotected intercourse |
Interventions |
Mife 25 mg, 2 doses, 12 h apart vs LNG 0.75 mg, 2 doses, 12 h apart vs Mife 25 mg, single dose vs Mife 25 mg + LNG 0.75 mg |
Outcomes |
Observed number of pregnancies, side effects and changes in menstrual pattern |
Notes |
Post‐randomisation exclusion and loss to follow‐up not reported
Observed pregnancy/expected pregnancy/total number women: Mife 25 mg twice 1/15/212; LNG 1/16/205; Mife 25 mg 3/13/182; Mife 25 + LNG 4/13/183
|
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Mentioned randomisation but description not adequate |
Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk |
Not mentioned |
Incomplete outcome data (attrition bias) All outcomes |
Unclear risk |
No mention of post‐randomisation exclusion and loss to follow‐up |
Selective reporting (reporting bias) |
Low risk |
Reported planned outcomes |
Other bias |
Low risk |
None detected |