NCT02577601

Trial name or title	Impact of combined hormonal contraceptives on UPA
Methods	Cross‐over assignment
Participants	Generally healthy women aged 18‐35 with regular menses (every 21‐35 days) Normal BMI Proven ovulation with a screening serum progesterone of > 3 ng/mL Willing to use condoms (if sexually active with a male partner), willing to not have sex with men during the study, or have had a tubal ligation (or have a partner who has had a vasectomy) or have a Cu‐IUD
Interventions	UPA vs LNG
Outcomes	Evidence of follicle rupture by day 5 following use of UPA
Starting date	5 August 2015
Contact information	Principal Investigator: Alison Edelman, MD Women's Health Research Unit whru@ohsu.edu
Notes

BMI: body mass index; Cu‐IUD: copper intrauterine device; EC: emergency contraception; IUS: intrauterine system; LNG: levonorgestrel; UPA: ulipristal acetate; UPT: urine pregnancy test