Methods |
Women were randomly allocated to 2 groups. Method of randomisation not reported |
Participants |
62 women attending in a family planning clinic, Liaoning Province. Women had regular menstrual periods and a single act of unprotected intercourse within 72 h of attending the clinic |
Interventions |
Mife 25 mg vs Mife 10 mg, single dose |
Outcomes |
Observed number of pregnancies, side effects and changes in menstrual pattern |
Notes |
Observed pregnancy/total number of women: Mife 25 mg: 1/30; Mife 10 mg: 1/32
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Side effects:
Mife 25 mg: nausea and vomiting 4/30; diarrhoea 4/30; dizziness 2/30; headache 4/30; fatigue 5/30
Mife 10 mg: nausea and vomiting 2/32; diarrhoea 2/32; dizziness 1/32; headache 3/32; fatigue 4/32
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Changes in menstrual pattern:
Mife 25 mg: delay: 29/29; spotting: 1/29
Mife 10 mg: delay: 30/31; spotting: 1/31
|
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Mentioned randomisation but description not adequate |
Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk |
Not mentioned |
Incomplete outcome data (attrition bias) All outcomes |
Unclear risk |
No mention of post‐randomisation exclusion and loss to follow‐up |
Selective reporting (reporting bias) |
Low risk |
Planned outcome of pregnancy rate was reported |
Other bias |
Low risk |
None detected |