Farajkhoda 2009

Methods	Women randomly allocated to 2 groups. Method of randomisation not reported
Participants	Prospective, randomised, comparative study, including 124 healthy volunteers who, in the observed cycle, had had only 1 act of unprotected intercourse within 72 h of treatment Randomly allocated to LNG (n = 62) and Yuzpe (n = 62)
Interventions	Yuzpe: involved 2 doses of combined oestrogen/progestin pills, with each dose containing 100 μg of ethinyl oestradiol and 500 μg of LNG LNG: LNG 0.75 mg taken within 72 h of unprotected coitus and LNG 0.75 mg taken 12 h later
Outcomes	Observed number of pregnancies, side effects and changes in menstrual pattern
Notes	Observed pregnancy/total number of women: Yuzpe: 5/60 (2 lost to follow‐up); LNG: 0/62 Side effects: Nausea: Yuzpe 41/60; LNG 4/62 Vomiting: Yuzpe 15/60; LNG 0/62 Headache: Yuzpe 13/60; LNG 0/62 Weakness: Yuzpe 10/60; LNG 1/62 Hot flushes: Yuzpe 4/60; LNG 2/62
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"Randomisation was done by randomisation schedules"‐ doesn't clarify what kind of schedule or how it was generated
Allocation concealment (selection bias)	Unclear risk	Does not state if there was any allocation concealment
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Does not state if blinding was present
Incomplete outcome data (attrition bias) All outcomes	Low risk	"Two women were excluded from the study because they were lost to follow‐up" Explains the lost participants as loss to follow‐up. Analysed all others
Selective reporting (reporting bias)	Unclear risk	The primary and secondary planned outcomes are not clearly stated in the methods and there is no protocol available to check.
Other bias	Low risk	None detected