Glasier 1992

Methods	Randomly allocated women to 2 treatment groups within predefined age groups (16‐25 years, 26‐34 years, 35‐45 years). Cards with the treatment names on were put in sealed envelopes and allocation was made by shuffling the cards. There was no blinding, placebos were not used. Side effects were assessed by women
Participants	800 women attending a family planning clinic and an accident and emergency department in Edinburgh, UK Included women with regular menstrual periods, aged 16‐45 years who had attended the clinic within 72 h of a single act of unprotected intercourse Excluded women on oral contraceptives, regular prescription drugs, with medical contraindications, who were difficult to follow up and who would continue with the pregnancy in case of a failure
Interventions	Yuzpe (ethinyl oestradiol 100 μg + norgestrel 1 mg, repeated after 12 h) vs Mife 600 mg, single dose
Outcomes	Observed number of pregnancies, side effects and changes in menstrual pattern
Notes	Loss to follow‐up: 26/800 (3.3%), 3 with Mife; 23 with Yuzpe Observed pregnancy/expected pregnancy rates not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Explanation for method of randomisation not provided
Allocation concealment (selection bias)	Unclear risk	Method of allocation concealment not explained
Blinding (performance bias and detection bias) All outcomes	Unclear risk	No mention of blinding
Incomplete outcome data (attrition bias) All outcomes	Low risk	Exclusions reported "26 women were lost to follow up" "A total of 693 women returned completed diary charts" (and were hence analysed)
Selective reporting (reporting bias)	Low risk	Planned variables were reported
Other bias	Low risk	None detected