Methods |
Women 'randomly allocated' to 3 groups. Method of randomisation not reported |
Participants |
300 healthy women in Beijing, China, with regular menstrual periods, aged 18‐48 years, with attended the clinic within 72 h of a single act of unprotected intercourse |
Interventions |
Mife 25 mg, orally, 2 doses, 12 h apart vs Mife 25 mg, orally, single dose, vs Mife 25 mg + anordrin 7.5 mg, single dose |
Outcomes |
Observed number of pregnancies, side effects and changes in menstrual pattern |
Notes |
Post‐randomisation exclusions or loss to follow‐up not reported
Observed pregnancy/expected pregnancy/total number of women: Mife 25 mg twice 0/7/100; Mife 25 mg single dose 1/6/99; Mife + anordrin 1/7/101
|
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Mentioned randomisation but description not adequate |
Allocation concealment (selection bias) |
Unclear risk |
Method of allocation concealment not mentioned |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk |
Not mentioned |
Incomplete outcome data (attrition bias) All outcomes |
Unclear risk |
No mention of post‐randomisation exclusion and loss to follow‐up |
Selective reporting (reporting bias) |
Low risk |
Planned outcome was reported |
Other bias |
Low risk |
None detected |