Comparison 9. Bupropion vs placebo ‐ rs1051730 ‐ non‐Hispanic black or African American.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Six‐Month Abstinence	2	124	Risk Ratio (M‐H, Random, 95% CI)	1.50 [0.75, 3.00]
1.1 Homozygous Major	2	92	Risk Ratio (M‐H, Random, 95% CI)	1.61 [0.71, 3.64]
1.2 Heterozygous	2	32	Risk Ratio (M‐H, Random, 95% CI)	1.30 [0.32, 5.34]
2 End of Treatment	3	157	Risk Ratio (M‐H, Random, 95% CI)	1.20 [0.70, 2.06]
2.1 Homozygous Major	3	117	Risk Ratio (M‐H, Random, 95% CI)	1.76 [0.96, 3.23]
2.2 Heterozygous	3	40	Risk Ratio (M‐H, Random, 95% CI)	0.68 [0.32, 1.44]