Comparison 14. Bupropion vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Six‐Month Abstinence	3	660	Risk Ratio (M‐H, Random, 95% CI)	1.30 [0.88, 1.92]
1.1 Homozygous Major	3	377	Risk Ratio (M‐H, Random, 95% CI)	1.17 [0.70, 1.98]
1.2 Heterozygous or Homozygous Minor	3	283	Risk Ratio (M‐H, Random, 95% CI)	1.44 [0.71, 2.91]
2 End of Treatment	4	693	Risk Ratio (M‐H, Random, 95% CI)	1.87 [1.36, 2.56]
2.1 Homozygous Major	4	395	Risk Ratio (M‐H, Random, 95% CI)	2.11 [1.39, 3.22]
2.2 Heterozygous or Homozygous Minor	4	298	Risk Ratio (M‐H, Random, 95% CI)	1.57 [0.93, 2.62]