Comparison 66. Bupropion ‐ rs1051730 ‐ non‐Hispanic white.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Six‐Month Abstinence	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Homozygous Major vs Homozygous Minor	4	316	Risk Ratio (M‐H, Random, 95% CI)	1.27 [0.67, 2.43]
1.2 Heterozygous vs Homozygous Minor	4	390	Risk Ratio (M‐H, Random, 95% CI)	1.15 [0.65, 2.03]
2 End of Treatment	6		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Homozygous Major vs Homozygous Minor	6	386	Risk Ratio (M‐H, Random, 95% CI)	1.15 [0.88, 1.50]
2.2 Heterozygous vs Homozygous Minor	6	480	Risk Ratio (M‐H, Random, 95% CI)	1.04 [0.81, 1.33]