Comparison 103. Placebo ‐ rs16969968 ‐ non‐Hispanic white.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Six‐Month Abstinence	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Homozygous Major vs Homozygous Minor	2	162	Risk Ratio (M‐H, Random, 95% CI)	1.05 [0.51, 2.14]
1.2 Heterozygous vs Homozygous Minor	2	211	Risk Ratio (M‐H, Random, 95% CI)	0.79 [0.32, 1.96]
2 End of Treatment	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Homozygous Major vs Homozygous Minor	4	218	Risk Ratio (M‐H, Random, 95% CI)	1.55 [0.68, 3.53]
2.2 Heterozygous vs Homozygous Minor	4	276	Risk Ratio (M‐H, Random, 95% CI)	1.34 [0.51, 3.53]