Comparison 107. Placebo ‐ rs2036527 ‐ non‐Hispanic white.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Six‐Month Abstinence	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Homozygous Major vs Homozygous Minor	2	160	Risk Ratio (M‐H, Random, 95% CI)	1.85 [0.77, 4.44]
1.2 Heterozygous vs Homozygous Minor	2	209	Risk Ratio (M‐H, Random, 95% CI)	1.58 [0.66, 3.77]
2 End of Treatment	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Homozygous Major vs Homozygous Minor	4	216	Risk Ratio (M‐H, Random, 95% CI)	1.98 [0.91, 4.35]
2.2 Heterozygous vs Homozygous Minor	4	275	Risk Ratio (M‐H, Random, 95% CI)	1.86 [0.94, 3.69]