| No. | Search terms | Results |
| 1 | (doctor* or physician* or nurse* or clinician* or consultant* or healthcare assistant* or health care assistant* or health care professional* or healthcare professional* or team* or healthcare worker* or health care worker* or (health* adj2 personnel) or medical or nursing or staff).ti,ab. | 1811863 |
| 2 | exp health personnel/ | 430936 |
| 3 | exp health facilities/ | 682773 |
| 4 | (ward? or centre or centres or center or centers or department? or unit or units or hospital?).ti,ab. | 1960472 |
| 5 | long‐term care.ti,ab. | 16518 |
| 6 | (residential adj3 (care or healthcare or facilit*)).ti,ab. | 4658 |
| 7 | nursing home?.ti,ab. | 25235 |
| 8 | 1 or 2 or 3 or 4 or 5 or 6 or 7 | 3711914 |
| 9 | hand disinfection/ | 4943 |
| 10 | (handwash* or hand wash* or hand hygiene or handrub* or hand rub*).ti,ab. | 6366 |
| 11 | (hand? adj2 (clean* or decontaminat* or disinfect* or hygiene or hygienic* or saniti* or sterili* or wash*)).ti,ab. | 6686 |
| 12 | (hand* adj3 (alcohol* or propanol* or ethanol*)).ti,ab. | 1322 |
| 13 | (hand* adj scrub*).ti,ab. | 101 |
| 14 | (antisepsis/ or sterilization/ or disinfection/) and hand/ | 432 |
| 15 | (hand? adj2 (aseps* or aseptic* or antisep*)).ti,ab. | 216 |
| 16 | or/9‐15 | 10437 |
| 17 | ((university adj student?) or school or preschool* or pre‐school* or daycare? or virolog* or parasitol* or home* or sanitat* or water).ti. | 344602 |
| 18 | 16 not 17 | 9861 |
| 19 | randomized controlled trial.pt. | 432907 |
| 20 | controlled clinical trial.pt. | 91818 |
| 21 | multicenter study.pt. | 212516 |
| 22 | pragmatic clinical trial.pt. | 427 |
| 23 | (randomis* or randomiz* or randomly).ti,ab. | 703141 |
| 24 | groups.ab. | 1648291 |
| 25 | (trial or multicenter or multi center or multicentre or multi centre).ti. | 192218 |
| 26 | (intervention? or effect? or impact? or controlled or control group? or (before adj5 after) or (pre adj5 post) or ((pretest or pre test) and (posttest or post test)) or quasiexperiment* or quasi experiment* or pseudo experiment* or pseudoexperiment* or evaluat* or time series or time point? or repeated measur*).ti,ab. | 7780288 |
| 27 | non‐randomized controlled trials as topic/ | 83 |
| 28 | interrupted time series analysis/ | 226 |
| 29 | controlled before‐after studies/ | 185 |
| 30 | or/19‐29 | 8697386 |
| 31 | exp animals/ | 20710394 |
| 32 | humans/ | 16384441 |
| 33 | 31 not (31 and 32) | 4325953 |
| 34 | review.pt. | 2202629 |
| 35 | meta analysis.pt. | 74283 |
| 36 | news.pt. | 180656 |
| 37 | comment.pt. | 686913 |
| 38 | editorial.pt. | 420754 |
| 39 | cochrane database of systematic reviews.jn. | 16245 |
| 40 | comment on.cm. | 686917 |
| 41 | (systematic review or literature review).ti. | 85309 |
| 42 | or/33‐41 | 7512404 |
| 43 | 30 not 42 | 6043658 |
| 44 | 8 and 16 and 43 | 3925304 |