Abrahams 2015.

Trial name or title	A randomised controlled trial of web‐based cognitive behavioral therapy for severely fatigued breast cancer survivors (CHANGE‐study)
Methods	Design: Multicentre RCT. N (Target) = 120 Follow‐up: baseline, after 6 months
Participants	Major inclusion criteria: Breast cancer survivors finished treatment at least 3 months previously, severely fatigued, able to assess internet
Interventions	E: Individual web‐based CBT, consisting of three face‐to‐face sessions and maximally eight web‐based modules over a period of 6 months; conducted by licensed cognitive behavioral therapists C: Care as usual
Outcomes	Quality of life (EORTC‐QLQ‐C30) Others CIS, SIP, BSI‐18
Starting date	NS
Contact information	Harriet.Abrahams@radboudumc.nl
Notes	E: experimental, C: comparison, RCT: randomised control trial, EORTC‐QLQ‐C30: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30; CIS: Fatigue severity; SIP: Functional impairments; BSI‐18: Psychological distress. The study is registered in the Dutch Trial Registry (reference no. NTR4309, date registered: December 6, 2013).