Summary of findings for the main comparison.
Bispectral index versus standard practice (risk of awareness in surgical patients with high risk of awareness) for improving anaesthetic delivery and postoperative recovery
| Bispectral index versus standard practice (risk of awareness in surgical patients with high risk of awareness) for improving anaesthetic delivery and postoperative recovery | ||||||
| Patient or population: patients for improving anaesthetic delivery and postoperative recovery Settings: Intervention: Bispectral index versus standard practice (risk of awareness in surgical patients with high risk of awareness) | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Control | Bispectral index versus standard practice (risk of awareness in surgical patients with high risk of awareness) | |||||
| Awareness in surgical patients with high risk of recall awareness ‐ using clinical signs as the guide in standard practice | Study population | OR 0.24 (0.12 to 0.48) | 7761 (4 studies) | ⊕⊕⊕⊝ moderate1,2 | ||
| 8 per 1000 | 2 per 1000 (1 to 4) | |||||
| Moderate | ||||||
| 8 per 1000 | 2 per 1000 (1 to 4) | |||||
| Awareness in surgical patients with high risk of recall awareness ‐ using end tidal anaesthetic gas as the guide | Study population | OR 1.13 (0.56 to 2.26) | 26530 (4 studies) | ⊕⊕⊝⊝ low1,3 | ||
| 1 per 1000 | 1 per 1000 (1 to 3) | |||||
| Moderate | ||||||
| 1 per 1000 | 1 per 1000 (1 to 2) | |||||
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; OR: Odds ratio | ||||||
| GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. | ||||||
1 clinical heterogeneity 2 OR < 0.5 3 wide 95% CI