Comparison 4.

Bispectral index versus clinical signs (requirement for narcotics)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Total dose of fentanyl (microgramme)	7	333	Mean Difference (IV, Random, 95% CI)	13.80 [‐19.80, 47.40]
2 average normalized remifentanil infusion rates ( microgramme/kg/min)	3	276	Mean Difference (IV, Fixed, 95% CI)	‐0.01 [‐0.02, ‐0.00]
3 Total dose of sufentanil ( microgramme)	1	40	Mean Difference (IV, Fixed, 95% CI)	‐33.80 [‐51.03, ‐16.57]