Study ID
Authors
MEDLINE Journal ID
Year of Publication
Language
Type of study	RCT Quasi‐RCT Non‐ RCT
Comments on study design
Does the study compare the use BIS (BIS group) and the use of clinical signs (SP group) in guiding doses of anaesthetics?
Was the assignment of subjects to treatment groups randomized?
Was there blinding? If so, who was blinded	Subject ‐Blinded? Yes/No/Unclear Anaesthesiologist Blinded? Yes/No/Unclear Outcome accessor blinded? Yes/No/Unclear
Were the BIS and SP groups similar at the start of the trial?
Apart from the treatment under investigation, were the groups treated equally?
Are all relevant outcomes measured in a standard, valid and reliable way?
What percentage of the individuals or clusters recruited into the study are included in the analysis?
Were all the subjects analysed in the groups to which they were randomly allocated?