Database	Time span	Search strategy	No of hits
The Cochrane Hepato‐Biliary Group Controlled Trials Register	November 2016.	(terlipressin* OR glypressin* OR vasoconstric*) AND hepatorenal syndrom*	31
The Cochrane Central Register of Controlled Trials (CENTRAL)	2016, Issue 11.	#1 MeSH descriptor: [Vasoconstrictor Agents] explode all trees #2 terlipressin* or glypressin* or vasoconstric* #3 #1 or #2 #4 MeSH descriptor: [Hepatorenal Syndrome] explode all trees #5 hepatorenal syndrom* #6 #4 or #5 #7 #3 and #6	35
MEDLINE Ovid	1946 to November 2016.	1. exp Vasoconstrictor Agents/ 2. (terlipressin* or glypressin* or vasoconstric*).mp. [mp=title, original title, abstract, name of substance word, subject heading word] 3. 1 or 2 4. exp Hepatorenal Syndrome/ 5. hepatorenal syndrom*.mp. [mp=title, original title, abstract, name of substance word, subject heading word] 6. 4 or 5 7. 6 and 3 8. (random* or blind* or placebo* or meta‐analysis).mp. [mp=title, original title, abstract, name of substance word, subject heading word] 9. 8 and 7	59
Embase Ovid	1974 to November 2016.	1. exp Terlipressin/ 2. exp Vasoconstrictor Agent/ 3. (terlipressin* or glypressin* or vasoconstric*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 4. 1 or 3 or 2 5. exp Hepatorenal Syndrome/ 6. hepatorenal syndrom*.mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 7. 6 or 5 8. 4 and 7 9. (random* or blind* or placebo* or meta‐analysis).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 10. 8 and 9	204
Science Citation Index Expanded (Web of Science)	1900 to November 2016.	#5 #4 AND #3 #4 TS=(random* or blind* or placebo* or meta‐analysis) #3 #1 AND #2 #2 TS=(hepatorenal syndrom*) #1 TS=(terlipressin* or glypressin* or vasoconstric*)	118