1 Rate of exacerbations requiring systemic corticosteroids |
2 |
936 |
Rate Ratio (Random, 95% CI) |
0.45 [0.36, 0.55] |
1.1 Eosinophilic |
2 |
936 |
Rate Ratio (Random, 95% CI) |
0.45 [0.36, 0.55] |
2 Rate of exacerbations requiring emergency department treatment or admission |
2 |
936 |
Rate Ratio (Random, 95% CI) |
0.36 [0.20, 0.66] |
2.1 Eosinophilic |
2 |
936 |
Rate Ratio (Random, 95% CI) |
0.36 [0.20, 0.66] |
3 Rate of exacerbations requiring admission |
2 |
936 |
Rate Ratio (Random, 95% CI) |
0.31 [0.13, 0.73] |
3.1 Eosinophilic |
2 |
936 |
Rate Ratio (Random, 95% CI) |
0.31 [0.13, 0.73] |
4 Health‐related quality of life (ACQ) |
2 |
936 |
Mean Difference (Random, 95% CI) |
‐0.42 [‐0.56, ‐0.28] |
4.1 Eosinophilic |
2 |
936 |
Mean Difference (Random, 95% CI) |
‐0.42 [‐0.56, ‐0.28] |
5 Health‐related quality of life (SGRQ) |
2 |
936 |
Mean Difference (Random, 95% CI) |
‐7.40 [‐9.50, ‐5.29] |
5.1 Eosinophilic |
2 |
936 |
Mean Difference (Random, 95% CI) |
‐7.40 [‐9.50, ‐5.29] |
6 Pre‐bronchodilator FEV1 (litres) |
2 |
936 |
Mean Difference (Random, 95% CI) |
0.11 [0.06, 0.17] |
6.1 Eosinophilic |
2 |
936 |
Mean Difference (Random, 95% CI) |
0.11 [0.06, 0.17] |
7 Serious adverse events |
2 |
936 |
Risk Ratio (M‐H, Random, 95% CI) |
0.63 [0.41, 0.97] |
7.1 Eosinophilic |
2 |
936 |
Risk Ratio (M‐H, Random, 95% CI) |
0.63 [0.41, 0.97] |
8 Adverse events leading to discontinuation |
2 |
936 |
Risk Ratio (M‐H, Random, 95% CI) |
0.45 [0.11, 1.80] |
8.1 Eosinophilic |
2 |
936 |
Risk Ratio (M‐H, Random, 95% CI) |
0.45 [0.11, 1.80] |