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. 2014 Feb 12;2014(2):CD003249. doi: 10.1002/14651858.CD003249.pub3

Comparison 4. Estrogen versus placebo/no treatment among women receiving conventional uterotonics for primary PPH.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Hysterectomy 1 112 Risk Ratio (M‐H, Fixed, 95% CI) 0.16 [0.01, 3.11]
2 Mean blood loss within two hours 1 112 Mean Difference (IV, Fixed, 95% CI) ‐274.9 [‐384.72, ‐165.08]
3 Mean blood loss between two and 24 hours 1 112 Mean Difference (IV, Fixed, 95% CI) ‐50.7 [‐83.07, ‐18.33]