Xu_M 2009.

Study characteristics
Patient sampling	Enrolment not reported
Patient characteristics and setting	172 inpatients; China Haematology department; non‐responsive fever Representative spectrum? Unclear: haematology department; non‐responsive fever. No information about enrollment and whether the study was prospective
Index tests	Platelia test; cut‐off single sample 0.7; or twice 0.5
Target condition and reference standard(s)	Criteria of the Editorial Board of the Chinese Journal of Medicine Incorporation avoided? Yes: Platelia explicitly excluded from criteria Acceptable reference standard? Unclear: Chinese criteria. The patients were divided into 3 groups: proven/probable; possible; no IA
Flow and timing	Timing not reported Partial verification avoided? Yes Withdrawals explained? No: not reported Uninterpretable results reported? No: not reported
Comparative
No patients per category	2 proven; 37 probable; 58 possible; 76 no IA
Notes	Not supported by Platelia Chinese language
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	Unclear
Was a case‐control design avoided?	Unclear
Did the study avoid inappropriate exclusions?	Unclear
		Unclear	Unclear
DOMAIN 2: Index Test All tests
Were the index test results interpreted without knowledge of the results of the reference standard?	Unclear
If a threshold was used, was it pre‐specified?	Unclear
		Unclear	Unclear
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	Unclear
Were the reference standard results interpreted without knowledge of the results of the index tests?	Unclear
		Unclear	Unclear
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Unclear
Did all patients receive the same reference standard?	Yes
Were all patients included in the analysis?	Unclear
		Unclear