Table 1.
Participant Characteristics by Quartile of Follicle Stimulating Hormone, Kuopio Ischaemic Heart Disease Risk Factor Study (1998–2001)
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||
|---|---|---|---|---|---|
| FSH Quartile (n) | (n=147) | (n=149) | (n=145) | (n=147) | |
| FSH range (IU/l) | 1–39.3 | 39.4–50.0 | 50.1–61.8 | 61.9 to 136.8 | |
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | P | |
| Age (yrs) | 64.5 (6.9) | 65.1 (5.9) | 64.4 (6.1) | 62.8 (6.9) | 0.02 |
| BMI (kg/m2) | 31.1 (5.7) | 29.0 (5.4) | 28.7 (5.0) | 26.8 (4.4) | <0.001 |
| WHR | 0.87 (0.07) | 0.85 (0.06) | 0.84 (0.06) | 0.83 (0.06) | <0.001 |
| Estradiol (pmol/ml) | 55.8 (77.6) | 35.1 (19.8) | 32.5 (12.5) | 34.1 (19.5) | <0.001 |
| Testosterone (nmol/l) | 1.5 (2.9) | 1.1 (0.5) | 1.1 (0.5) | 1.1 (0.5) | 0.062 |
| SHBG (nmol/L) | 45.6 (23.2) | 49.5 (21.2) | 55.0 (24.3) | 58.4 (28.0) | <0.001 |
| SBP (mmHg) | 140.8 (20.4) | 141.1 (17.3) | 136.2 (16.4) | 135.8 (16.4) | 0.01 |
| DBP (mmHg) | 80.9 (9.7) | 80.5 (8.7) | 79.6 (8.3) | 80.4 (8.5) | 0.66 |
| Physical Activity (MET-hr/day) | 45.2 (5.9) | 46.1 (7.1) | 46.3 (6.1) | 47.4 (7.5) | 0.05 |
| Parity | 2.8 (1.4) | 2.7 (1.6) | 2.8 (1.7) | 2.3 (1.3) | 0.08 |
| n (%) | n (%) | n (%) | n (%) | P | |
| Age at menopause (yrs) | 49.7 (4.4) | 49.4 (4.3) | 48.9 (4.8) | 49.2 (4.3) | 0.50 |
| Current Smoker | 12 (8%) | 14 (9%) | 16 (11%) | 7 (5%) | 0.25 |
| Past Smoker | 19 (13%) | 15 (10%) | 11 (8%) | 19 (13%) | 0.37 |
| Past HT use | 38 (26%) | 45 (30%) | 48 (33%) | 49 (33%) | 0.58 |
SD: standard deviation, FSH: follicle stimulating hormone, BMI: body mass index, SHBG: sex hormone binding globulin, SBP: systolic blood pressure, DBP: diastolic blood pressure: HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol, HT: hormone therapy