Table 3:

Follicle Stimulating Hormone and Mean Lipid Levels in Postmenopausal Women, Stratified by Age, Kuopio Ischaemic Heart Disease Risk Factor Study (1998–2001).

	Ages 53 to 62 years (n = 244)				Ages 64–73 years (n = 344)
	Mean (SD) ^a	Beta^b	SE	P	Mean (SD) ^a	Beta^b	SE	P
Total Cholesterol
FSH Q1	5.6 (0.7)		Ref		5.5 (0.8)		Ref
FSH Q2	5.8 (1.0)	0.023	0.013	0.11	5.7 (1.0)	0.005	0.011	0.64
FSH Q3	5.8 (0.9)	0.026	0.013	0.06	5.7 (0.8)	0.008	0.011	0.49
FSH Q4	5.9 (1.0)	0.021	0.013	0.10	6.0 (1.0)	0.024	0.012	0.06
p for trend				0.22				0.05
LDL-C
FSH Q1	3.6 (0.7)		Ref		3.6 (0.7)		Ref
FSH Q2	3.8 (1.0)	0.022	0.022	0.33	3.8 (1.0)	0.002	0.016	0.89
FSH Q3	3.8 (0.9)	0.048	0.021	0.03	3.7 (0.8)	0.003	0.017	0.84
FSH Q4	3.9 (1.0)	0.041	0.021	0.05	3.9 (1.0)	0.026	0.019	0.16
p for trend				0.14				0.01
HDL-C
FSH Q1	1.3 (0.3)		Ref		1.2 (0.3)		Ref
FSH Q2	1.3 (0.3)	0.027	0.018	0.13	1.3 (0.3)	0.011	0.016	0.48
FSH Q3	1.4 (0.3)	0.014	0.017	0.42	1.4 (0.3)	0.024	0.017	0.15
FSH Q4	1.4 (0.3)	0.008	0.017	0.57	1.4 (0.4)	0.022	0.018	0.23
p for trend				0.42				0.09
Triglycerides
FSH Q1	1.4 (0.7)		Ref		1.4 (0.7)		Ref
FSH Q2	1.4 (0.8)	-0.018	0.035	0.61	1.4 (0.6)	0.032	0.026	0.23
FSH Q3	1.2 (0.6)	-0.001	0.033	0.98	1.2 (0.6)	0.021	0.028	0.46
FSH Q4	1.2 (0.6)	0.044	0.032	0.17	1.2 (0.6)	0.030	0.030	0.32
p for trend				0.54				0.28

FSH: follicle stimulating hormone, Q: quartile, SE: standard error;

Unadjusted, untransformed mean total cholesterol (mmol/L), low-density lipoprotein cholesterol (LDL-C, mmol/L), high-density lipoprotein-cholesterol (HDL-C, mmol/L), and triglycerides (mmol/l).

Lipid levels log transformed to improve normality in all regression models. Model adjusted for age (continuous), year of study entry (continuous), estradiol (quartiles), testosterone (quartiles), sex-hormone binding globulin (quartiles), age at menarche (above and below median), last menstruation age (above and below median), duration of oral contraceptive use (above and below median), duration of hormone therapy use (above and below median), history of hysterectomy (yes, no), history of oophorectomy (yes, no).

systolic blood pressure (continuous), diastolic blood pressure (continuous), smoking status (never, past, current + pack-years above median; current + pack-years below median), physical activity (quartiles), body mass index (continuous), waist-to-hip ratio (continuous), and use of lipid lowering medication (yes, no)