Table 4.
Association of Follicle Stimulating Hormone and Abnormal Lipid Level in Postmenopausal Women, Kuopio Ischaemic Heart Disease Risk Factor Study (1998–2001).
| n | beta per 1 IU higher FSHc | SE | OR per 10 IU higher FSH | 95% Confidence Interval | P | |
|---|---|---|---|---|---|---|
| Dyslipidemia (all lipids) a,b | ||||||
| No | 296 | reference | ||||
| Yes | 292 | 0.003 | 0.005 | 1.03 | 0.94–1.13 | 0.57 |
| Total Cholesterolb | ||||||
| ≤ 6.2 mmol/La | 399 | reference | ||||
| > 6.2 mmol/L | 189 | 0.012 | 0.005 | 1.13 | 1.02–1.24 | 0.02 |
| LDL-Cb | ||||||
| < 4.1 mmol/La | 374 | reference | ||||
| ≥ 4.1 mmol/L | 214 | 0.011 | 0.005 | 1.12 | 1.01–1.23 | 0.03 |
| HDL-Cb | ||||||
| ≥ 1.0 mmol/La | 491 | reference | ||||
| < 1.0 mmol/L | 97 | -0.010 | 0.007 | 0.90 | 0.78–1.04 | 0.15 |
| Triglyceridesb | ||||||
| < 2.3 mmol/La | 520 | reference | ||||
| ≥ 2.3 mmol/L | 68 | -0.012 | 0.008 | 0.89 | 0.75–1.05 | 0.17 |
OR: odds ratio; SE: standard error
a
Lipid classifications based on ATP III guidelines9.
b
Case status also includes use of lipid-lowering medication
c
Adjusted for age (continuous), date of study entry, sex hormone binding globulin (continuous), estradiol (continuous), body mass index (continuous), and waist to hip ratio (continuous).