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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Arthritis Rheumatol. 2019 Apr 2;71(5):712–721. doi: 10.1002/art.40834

Table 3-.

Association of healthcare access and geographic region with long-term pre-operative opioid use rates in in a cohort of severe osteoarthritis patients, Medicare data 2010–2014

Independent variables of interest N (%) of PCSAs (total N= 4,080) Unadjusted mean (SD) of % long-term opioid users Adjusted*mean difference in proportion (percentage points) of long term opioid users (95% confidence interval)
State
New York 181 (4.4) 12.3 (6.1) Reference
West Virginia 26 (0.6) 24.9 (8.6) 10.3 (7.9–12.6)
Alabama 69 (1.7) 26.4 (7) 10.2 (7.3–13.2)
Georgia 111 (2.7) 22.9 (8.2) 9.4 (6.8–12)
Kentucky 81 (2) 24 (9.6) 8.8 (7.2–10.4)
Lousiana 53 (1.3) 25 (8.6) 8.3 (6.5–10.1)
Oklohama 77 (1.9) 22.3 (6.1) 8.2 (6.6–9.8)
North Carolina 135 (3.3) 22.6 (8.1) 7.9 (5.5–10.3)
Virginia 123 (3) 17 (6.3) 7.2 (5.8–8.7)
Inidiana 128 (3.1) 19.1 (6.1) 7.2 (5.8–8.6)
Mississipi 67 (1.6) 25 (7.7) 7.1 (4.5–9.7)
Number of primary care providers/1000 Medicare beneficiaries in the primary care service area
>8.6 (Q4) 1020 (25) 16 (7.2) Reference
5.5–8.6 (Q3) 1020 (25) 16.4 (7.2) 0.9 (0.4–1.4)
3.6–5.5 (Q2) 1020 (25) 18.3 (8.0) 1.7 (1.1–2.2)
<3.6 (Q1) 1020 (25) 18.3 (8.5) 1.4 (0.8–2)
Number of rheumatologists/1000 Medicare beneficiaries in the primary care service area
>0.29 (T3) 381 (9.4) 15.4 (7.2) Reference
0.15–0.29 (T2) 381 (9.4) 16.3 (6.4) 0.4 (−0.4–1.2)
<0.15 (T1) 381 (9.3) 17.5 (6.0) 0.1 (−0.8–0.9)
None 2938 (72) 17.6 (8.2) 0.6 (−0.1–1.3)
*

Adjusted for case-mix including age, race, gender, dual Medicare-Medicaid enrollment, pain related diagnoses, co-morbid conditions, type of joint replacement surgery, and socioeconomic characteristics in each primary care service area as well as state level policies including rigor of prescription drug monitoring programs and legal availability of medical marijuana.

Based on the highest adjusted estimates, top 10 states presented in descending order of the magnitude of the effect. New York was selected as the reference based on low proportion of long term opioid users and a large sample size. Estimates for rest of the states are provided in Appendix Table 1.