Table 1.
Patient cohort information
| Number of patients | 108 |
| Age (years) | 65 ± 17.3 |
| Male | 57 (52.8) |
| Trauma mechanism | |
| Fall | 58 (53.7) |
| Assault | 5 (4.6) |
| Motor vehicle accident | 12 (11.1) |
| Fall from bike | 12 (11.1) |
| Other | 21 (19.4) |
| TBI severity | |
| Very severe (GCS3–5) | 22 (20.4) |
| Severe (GCS3–8) | 49 (45.4) |
| Moderate (GCS9–12) | 19 (17.6) |
| Mild (GCS13–15) | 40 (37.0) |
| Clinical parameters | |
| GCS score | 9.63 ± 4.3 |
| Pupil abnormality* | 27 (26.7) |
| Focal neurologic symptoms | 42 (38.9) |
| Major extracranial injury | 12 (11.1) |
| CT parameters | |
| Thickness (mm) | 13.6 ± 6.1 |
| Midline shift (mm) | 11.4 ± 6.6 |
| Concomitant lesion | 48 (44.4) |
| Basal cisterns compressed | 39 (36.1) |
| Treatment | |
| Conservative | 18 (16.7) |
| Emergent surgical intervention: | 90 (83.3) |
| Craniotomy | − 60 (55.6) |
| Decompressive craniectomy (DC) | − 29 (26.9) |
| ICP monitoring | − 40 (37.0) |
| In-hospital mortality | 41 (37.9) |
| Functional outcome | |
| GOS1–3 (unfavorable) | 56 (51.9) |
| GOS4–5 (favorable) | 50 (46.3) |
| Missing GOS | 2 (1.9) |
| QOLIBRI response | |
| FU time, months | 46 ± 16 |
| Yes | 25 (23.1) |
| No (died; too disabled) | 53 (48; 5) |
| No, other | 30 (27.8) |
Table 1 provides general information about the patient cohort. Legend: N (%) or mean ± SD, unless stated otherwise
SD, standard deviation; GCS, Glasgow Coma Score; CT, computed tomography; DC, decompressive craniectomy; ICP, intracranial pressure; GOS, Glasgow Outcome Score; QOLIBRI, quality of life after brain injury; FU, follow-up
*At least one pupil unresponsive to light upon arrival in the emergency room (missing for seven patients)