. 2019 Apr 25;9:6569. doi: 10.1038/s41598-019-42982-5

Table 2.

Changes at 12 Months and 24 Months after Initial Ranibizumab Injection.

	BL	12 M	24 M	P values
				ANOVA	Post hoc
				ANOVA	BLvs12M	BLvs24M
Mean logMAR VA	0.28 ± 0.27	0.03 ± 0.14	0.03 ± 0.16	<0.001	<0.001	<0.001
Foveal thickness (μm)	495.6 ± 141.0	286.1 ± 65.8	289.9 ± 68.4	<0.001	<0.001	<0.001
Total NPA (disc area)	14.0 ± 16.8	33.1 ± 32.9	—	N. A.	<0.001	N. A.
Central Macular NPA in SCP (mm²)	1.53 ± 0.59	1.59 ± 0.55	1.46 ± 0.50	0.891	N. A.	N. A.
Central Macular NPA in DCP (mm²)	1.79 ± 0.69	1.82 ± 0.66	1.75 ± 0.54	0.780	N. A.	N. A.

BL = baseline; VA = visual acuity; M = months; NPA = retinal nonperfusion area; ANOVA = repeated measures analysis of variance. To avoid segmentation errors, the baseline measurements of optical coherence tomography angiography were obtained after the initial resolution of macular edema.