Table 1.
In vitro hepatocyte function.
| Parameter | Overnight | Day 2 | Day 4 | Day 6 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean ± SEM | p-Value | Mean ± SEM | p-Value | Mean ± SEM | p-Value | Mean ± SEM | p-Value | |||||
| Percoll− | Percoll+ | Percoll− | Percoll+ | Percoll− | Percoll+ | Percoll− | Percoll+ | |||||
| Urea (mg/dL) | 12.74 ± 2.30 | 9.84 ± 1.03 | 0.0532 | 11.71 ± 1.89 | 9.61 ± 1.12 | 0.2722 | 9.83 ± 1.70 | 8.10 ± 0.83 | 0.3205 | 8.18 ± 0.81 | 7.63 ± 0.69 | 0.1111 |
| Albumin (ng/mL) | 1843.41 ± 529.30 | 1884.05 ± 466.00 | 0.8906 | 1817.28 ± 542.40 | 1625.02 ± 215.40 | 0.3683 | 897.36 ± 259.00 | 1474.38 ± 363.20 | 0.0004 | 716.08 ± 192.82 | 835.26 ± 191.45 | 0.3225 |
| AST (U/L) | 82.37 ± 18.67 | 52.71 ± 6.13 | 0.0090 | 36.56 ± 4.27 | 31.56 ± 3.83 | 0.0516 | 29.38 ± 6.67 | 22.14 ± 1.96 | 0.3525 | 29.98 ± 2.96 | 33.77 ± 3.62 | 0.0425 |