Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 25;9:6403. doi: 10.1038/s41598-019-42833-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Comparisons of paired-pulse facilitation (PPF) ratios under basal conditions and after the induction of long-term potentiation (LTP) in 4-week-old WT and SNAP-25b-deficient (MT) male mice. (a) Mean PPF ratios across different intervals tested become significantly lower with the induction of LTP in WT male mice (*p < 0.05, Student’s t-test, n = 9). (b) Mean PPF ratios become significantly lower with the induction of LTP in MT male mice across different time intervals as well (*p < 0.05, Student’s t-test, n = 11,). (c,d) MT male mice exhibited a non-significant trend towards higher PPF ratios compared to WT, under basal conditions (p = 0.09, Student’s t-test) and no significant changes in PPF ratios were observed between WT and MT male mice after the induction of LTP (p = 0.14, Student’s t-test). All error bars represent ± s.e.m.