Table 2.

Survival of S. boulardii subjected unencapsulated or encapsulated to simulated gastrointestinal digestion

	Free yeasts		Encapsulated yeasts
	CFU (mL)	Survival (%)	CFU (mL)	Survival (%)
Initial amount	1.95 × 108	–	9.96 × 107	–
Controls (pH 6.5 for 10.25 h)	7.2 × 107	37.0	3.3 × 107	33.4
Simulated digestion (10.25 h)a	4.3 × 106	2.2	3.3 × 106	3.4

Probiotic yeasts were stored for 12 h at 4 °C prior to simulated gastrointestinal digestion

^aSimulated gastrointestinal digestion consisted of five compartments with a specific pH value and incubation time for each compartment. Pepsin, pancreatin and bile salts were added as indicated in Table 1