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TNFα binding to anionic biopolymers DNA and heparin. A, inhibition of the binding of TNFα to a negatively charged biosensor surface by DNA and heparin. B and C, binding kinetics of the mixture of TNFα (1 μm) with various concentration of S-DNA (B) and several DNA structures or heparin at 1 μm (C) to a negatively charged sensor.
