Table 1.
Neurobehavioral test
| Neurobehavioral Items | Behavioral Test | Score | |
|---|---|---|---|
| Motor tests | Raising the mouse by the tail | Flexion of forelimb | 1 |
| Flexion of hindlimb | 1 | ||
| Head moved >10 ° to vertical axis within 30 s | 1 | ||
| Inability to walk straight | 1 | ||
| Placing the mouse on the floor | Circling toward the paretic side | 1 | |
| Falling down to the paretic side | 1 | ||
| Immobility and staring | 1 | ||
| Abnormal movements | Tremor (wet-dog-shakes) | 1 | |
| Myodystony, irritability, seizures, myoclonus | 1 | ||
| Sensory tests Visual and tactile placing (limb placing test to detect visual and superficial sensory) | Moving the mouse laterally toward the table | Reaching the table slowly with limbs or cannot place at all | 1 |
| Proprioceptive test (deep sensory), pushing the paw against the table edge to stimulate limb muscles | Losing the resistance Reflexes | 1 | |
| Absence of pinna reflex (a head shake when touching the auditory meatus) | 1 | ||
| Absence of corneal reflex (an eye blink when lightly touching the cornea with cotton) | 1 | ||
| Absence of startle reflex (a motor response to a brief loud noise from snapping a clipboard paper) | 1 | ||
| Maximum points | 14 | ||
Beam balance test