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. 2019 Feb 22;23(5):3325–3335. doi: 10.1111/jcmm.14223

Figure 7.

Figure 7

Schematic representation showing that β‐arrestin2 (ARRB2) negatively regulated NOD2 signalling pathway through the association with TRAF6 in cerebral ischaemia/reperfusion injury. MDP stimulation promoted the formation of ARRB2/TRAF6 complex which suppressed NF‐κB/COX‐2/MMP‐9 signalling